US Molecular: Recent Topics

US Molecular: Recent Topics http://www.usmolecular.com/forum/ Molecular Imaging for Life en Thu, 29 Jul 2010 17:57:37 +0000 v78q2zqd76fqfr on "MUGA" http://www.usmolecular.com/forum/topic/muga#post-15 Tue, 26 May 2009 11:02:42 +0000 v78q2zqd76fqfr 15@http://www.usmolecular.com/forum/ protocol from the Association of Nuclear Medicine Physicians of India <a href="http://www.anmpi.org/anmpi/caseofmonth/ImagingProtocolsFULL.asp?id=295" rel="nofollow">http://www.anmpi.org/anmpi/caseofmonth/ImagingProtocolsFULL.asp?id=295</a> protocol from the society of nuclear medicine <a href="http://interactive.snm.org/docs/pg_ch01_0403.pdf" rel="nofollow">http://interactive.snm.org/docs/pg_ch01_0403.pdf</a> v78q2zqd76fqfr on "ACC Appropriateness Criteria for Nuclear Cardiolgoy" http://www.usmolecular.com/forum/topic/acc-appropriateness-criteria-for-nuclear-cardiolgoy#post-14 Tue, 26 May 2009 00:19:54 +0000 v78q2zqd76fqfr 14@http://www.usmolecular.com/forum/ ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM 2009 Appropriate Use Criteria for Cardiac Radionuclide Imaging. A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine. Hendel RC, Berman DS, Di Carli MF, Heidenreich PA, Henkin RE, Pellikka PA, Pohost GM, Williams KA. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19451357" rel="nofollow">http://www.ncbi.nlm.nih.gov/pubmed/19451357</a> v78q2zqd76fqfr on "Cardiac computed tomographic angiography in an outpatient setting" http://www.usmolecular.com/forum/topic/cardiac-computed-tomographic-angiography-in-an-outpatient-setting#post-13 Mon, 25 May 2009 23:52:44 +0000 v78q2zqd76fqfr 13@http://www.usmolecular.com/forum/ J Cardiovasc Comput Tomogr. 2009 Mar-Apr;3(2):90-5. Epub 2009 Jan 29.Links Cardiac computed tomographic angiography in an outpatient setting: an analysis of clinical outcomes over a 40-month period. Gopal A, Nasir K, Ahmadi N, Gul K, Tiano J, Flores M, Young E, Witteman AM, Holland TC, Flores F, Mao SS, Budoff MJ. Los Angeles Biomedical Research Institute at Harbor-UCLA, 1124 W. Carson Street, RB2, Torrance, CA 90502, USA. BACKGROUND: Cardiac computed tomographic angiography (CTA) provides for accurate noninvasive diagnosis of coronary artery disease (CAD). OBJECTIVES: We analyzed the clinical outcomes over 40 months in patients with and without CAD as determined by CTA in an outpatient setting. METHODS: Consecutive symptomatic patients (n = 493; mean age, 58 +/- 15 years; 70% men) with an intermediate likelihood of CAD referred for outpatient CTA evaluation were prospectively followed for a mean of 40 +/- 9 months. RESULTS: Results of CTA included as normal (defined as normal coronary lumen), found in 32% (157), nonobstructive disease (<50% luminal stenosis) in 41% (204), obstructive disease (>or=50% luminal stenosis) in 19% (93). Eight percent (n = 39) had >or=1 major nondiagnostic coronary artery segment. Follow-up identified 21 patients with myocardial infarction (MI) in the significant obstructive CAD and nondiagnostic group. No patients with either normal coronary arteries or nonobstructive disease experienced an MI during follow-up. The 40-month event-free survival was 100% for both the normal and nonobstructive disease groups, 97.5% for the nondiagnostic study group, and 79% for the group with obstructive CAD. After adjustment for age, sex, diabetes mellitus, hypertension, hypercholesterolemia, and baseline coronary artery calcium (CAC), a stepwise multivariable model (Cox regression) showed that obstructive CAD was an independent predictor of cardiac events and had significant incremental value over clinical risk factors and CAC (HR = 16.6; 95% CI, 4.9-55.2; P = 0.0001). CONCLUSION: In symptomatic patients with an intermediate likelihood of CAD referred for CTA, normal coronary arteries or nonobstructive CAD portends an excellent prognosis. The finding of obstructive CAD identifies patients at higher risk of subsequent MI, independent of cardiovascular risk factors and coronary artery calcium. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19269915" rel="nofollow">http://www.ncbi.nlm.nih.gov/pubmed/19269915</a> v78q2zqd76fqfr on "J Nucl Cardiol: Stress single photon emission computed tomography for detection" http://www.usmolecular.com/forum/topic/j-nucl-cardiol-stress-single-photon-emission-computed-tomography-for-detection#post-12 Mon, 25 May 2009 23:45:46 +0000 v78q2zqd76fqfr 12@http://www.usmolecular.com/forum/ Stress single photon emission computed tomography for detection of coronary artery disease and risk stratification of asymptomatic patients at moderate risk. Khandaker MH, Miller TD, Chareonthaitawee P, Wells Askew J, Hodge DO, Gibbons RJ. Division of Cardiovascular Diseases, Mayo Clinic, Gonda 5, 200 First Street SW, Rochester, MN, 55905, USA. BACKGROUND: The American College of Cardiology Foundation/American Society of Nuclear Cardiology appropriateness criteria document assigns single photon emission computed tomography myocardial perfusion imaging (SPECT MPI) a rating of uncertain for detection and risk assessment of coronary artery disease (CAD) in asymptomatic patients at moderate risk. METHODS AND RESULTS: The nuclear cardiology database was used to identify 260 asymptomatic patients (67 +/- 8 years, 72% men) without known CAD who were at moderate CAD risk according to the Framingham risk score. SPECT MPI images were categorized using the summed stress score (SSS). Mean follow-up 9.9 +/- 3.0 years. Abnormal SPECT MPI scans were present in 142 patients (55%). By SSS categories, SPECT scans were low-risk in 67%, intermediate-risk in 20%, and high-risk in 13% of patients. Overall survival at 10 years was 79%, significantly better than the age- and gender-matched Minnesota general population (P < 0.001). Survival was 60% for patients with high-risk scans (95% CI 45-80%), 79% with intermediate-risk scans (95% CI 69-91%), and 83% with low-risk scans (95% CI 77-88%) (P = 0.03), including 84% (95% CI 77-91%) with normal scans. CONCLUSIONS: In this retrospectively identified group of asymptomatic patients at moderate CAD risk, stress SPECT MPI was effective for the detection and risk stratification of CAD. Average annual mortality was 4.0% in patients with high-risk scans vs 1.6% in patients with normal scans. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19440807" rel="nofollow">http://www.ncbi.nlm.nih.gov/pubmed/19440807</a> v78q2zqd76fqfr on "JNM: Vascular Inflammation Imaging with 18F-FDG PET/CT: When to Image?" http://www.usmolecular.com/forum/topic/vascular-inflammation-imaging-with-18f-fdg-petct-when-to-image#post-11 Mon, 25 May 2009 23:30:18 +0000 v78q2zqd76fqfr 11@http://www.usmolecular.com/forum/ Menezes LJ, Kotze CW, Hutton BF, Endozo R, Dickson JC, Cullum I, Yusuf SW, Ell PJ, Groves AM. Institute of Nuclear Medicine, University College Hospital, University College London, London, United Kingdom. We prospectively investigated the ideal imaging time to measure vascular uptake after injection of (18)F-FDG. METHODS: A total of 17 patients with atherosclerotic abdominal aortic aneurysm underwent dynamic abdominal PET/CT using 2-min frames between 45 and 53, 57 and 65, 115 and 123, and 175 and 183 min after injection of (18)F-FDG. For each period of dynamic imaging, vessel wall and lumen uptake were measured using the maximum standardized uptake value (SUVmax) and target-to-background ratio (TBR). RESULTS: No significant difference in TBR across all time points (repeated measures ANOVA, P = 0.206) was observed, despite a significant difference in aortic wall and lumen uptake with time (repeated measures ANOVA, P = 0.02 and P < 0.001, respectively). There was no significant difference between aortic wall uptake at 60 min (SUVmax, 2.15 +/- 0.11 SE) and 180 min (SUVmax, 1.99 +/- 0.18 SE) (paired t test, P = 0.367). There was a significant difference in lumen uptake at 60 min (SUVmax, 2.4 +/- 0.11 SE) and 180 min (SUVmax, 1.7 +/- 0.1 SE) (paired t test, P = 0.001). There was no significant difference in TBR between 60 min (0.91 +/- 0.03) and 180 min (1.01 +/- 0.06 SE) (paired t test, P = 0.131). With increasing delayed imaging, there was increasing variability (SE) in the SUVmax for the aortic wall and TBRs. CONCLUSION: There was no significant advantage in imaging at 3 h over 1 h after (18)F-FDG injection. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19443587" rel="nofollow">http://www.ncbi.nlm.nih.gov/pubmed/19443587</a> v78q2zqd76fqfr on "Newsletter Signup" http://www.usmolecular.com/forum/topic/newsletter-signup#post-9 Mon, 25 May 2009 17:36:59 +0000 v78q2zqd76fqfr 9@http://www.usmolecular.com/forum/ To signup for our newsletter, send an email to: <a href="mailto:usmolecular@SubscribeMeNow.com">usmolecular@SubscribeMeNow.com</a> or visit: <a href="http://www.usmolecular.com/newsletter.php" rel="nofollow">http://www.usmolecular.com/newsletter.php</a> If you have been automatically directed to this page, there may have been an error with your signup. 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This Agreement will be binding upon and will inure to the benefit of the parties, their successors and permitted assigns. v78q2zqd76fqfr on "Privacy Policy" http://www.usmolecular.com/forum/topic/privacy-policy#post-3 Mon, 25 May 2009 13:05:46 +0000 v78q2zqd76fqfr 3@http://www.usmolecular.com/forum/ Privacy Policy Your privacy is critically important to us. At USMolecular we have a few fundamental principles: * We don’t ask you for personal information unless we truly need it. (We can’t stand services that ask you for things like your gender or income level for no apparent reason.) * We don’t share your personal information with anyone except to comply with the law, develop our products, or protect our rights. * We don’t store personal information on our servers unless required for the on-going operation of one of our services. Below is our privacy policy which incorporates these goals: USMolecular (“USMolecular”) operates several websites including USMolecular.com. It is USMolecular’s policy to respect your privacy regarding any information we may collect while operating our websites. Website Visitors Like most website operators, USMolecular collects non-personally-identifying information of the sort that web browsers and servers typically make available, such as the browser type, language preference, referring site, and the date and time of each visitor request. USMolecular’s purpose in collecting non-personally identifying information is to better understand how USMolecular’s visitors use its website. From time to time, USMolecular may release non-personally-identifying information in the aggregate, e.g., by publishing a report on trends in the usage of its website. USMolecular also collects potentially personally-identifying information like Internet Protocol (IP) addresses. USMolecular does not use such information to identify its visitors, however, and does not disclose such information, other than under the same circumstances that it uses and discloses personally-identifying information, as described below. Gathering of Personally-Identifying Information Certain visitors to USMolecular’s websites choose to interact with USMolecular in ways that require USMolecular to gather personally-identifying information. The amount and type of information that USMolecular gathers depends on the nature of the interaction. For example, we ask visitors who sign up for a blog at USMolecular.com to provide a username and email address. Those who engage in transactions with USMolecular – by purchasing access to the Akismet comment spam prevention service, for example – are asked to provide additional information, including as necessary the personal and financial information required to process those transactions. 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USMolecular encourages visitors to frequently check this page for any changes to its Privacy Policy. If you have a USMolecular.com account, you should also check your blog’s dashboard for alerts to these changes. Your continued use of this site after any change in this Privacy Policy will constitute your acceptance of such change. v78q2zqd76fqfr on "SNM Annual Meeting 2009" http://www.usmolecular.com/forum/topic/snm-annual-meeting-2009#post-2 Sat, 23 May 2009 13:01:44 +0000 v78q2zqd76fqfr 2@http://www.usmolecular.com/forum/ This is a demonstration forum for the SNM Annual Meeting 2009 held in Toronto. 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